PETLiverUptakeMeasurement: Automated measurement of liver uptake in PET

3D Slicer extension for automated measurement of liver uptake in PET scans


PETLiverUptakeMeasurement is an extension of 3D Slicer that allows automated measurement of liver uptake in SUV normalized whole-body FDG-18 PET scans and export to DICOM. The extension provides the automated algorithm, a GUI module for providing additonal input, and functionality to export quantification results to DICOM SEG and SR files.


Installation: PETLiverUptakeMeasurement can be installed as an extension to 3D Slicer via 3D Slicer Extension manager. In addition to the GUI module, the extension includes a command line interface module, PETLiverUptakeMeasurementCLI, which can be used in batch mode.

Documentation: link

Source code: link


  • Bauer C, Sun S, Sun W, et al. Automated measurement of uptake in cerebellum, liver, and aortic arch in full-body FDG PET/CT scans. Med Phys. 2012;39(6):3112-3123 link - This publication describes in detail the algorithm implemented in the module, and its evaluation in a clinical dataset.

  • Fedorov A, Clunie D, Ulrich E, et al. DICOM for quantitative imaging biomarker development: a standards based approach to sharing clinical data and structured PET/CT analysis results in head and neck cancer research. PeerJ. 2016;4:e2057 link - This publication describes the dataset that includes segmentations produced using the PETTumorSegmentation tool.

Grants support

  • U01 CA140206
  • U24 CA180918

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