About

PETLiverUptakeMeasurement is an extension of 3D Slicer that allows automated measurement of liver uptake in SUV normalized whole-body FDG-18 PET scans and export to DICOM. The extension provides the automated algorithm, a GUI module for providing additonal input, and functionality to export quantification results to DICOM SEG and SR files.

Availability

Installation: PETLiverUptakeMeasurement can be installed as an extension to 3D Slicer via 3D Slicer Extension manager. In addition to the GUI module, the extension includes a command line interface module, PETLiverUptakeMeasurementCLI, which can be used in batch mode.

Documentation: link

Source code: link

Publications

• Bauer C, Sun S, Sun W, et al. Automated measurement of uptake in cerebellum, liver, and aortic arch in full-body FDG PET/CT scans. Med Phys. 2012;39(6):3112-3123 link - This publication describes in detail the algorithm implemented in the module, and its evaluation in a clinical dataset.

• Fedorov A, Clunie D, Ulrich E, et al. DICOM for quantitative imaging biomarker development: a standards based approach to sharing clinical data and structured PET/CT analysis results in head and neck cancer research. PeerJ. 2016;4:e2057 link - This publication describes the dataset that includes segmentations produced using the PETTumorSegmentation tool.

Grants support

• U01 CA140206
• U24 CA180918